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載脂蛋白B-mRNA編輯酶復(fù)合物1抗體

文字:[大][中][小] 2017-5-4    瀏覽次數(shù):1122    

                                載脂蛋白B-mRNA編輯酶復(fù)合物1抗體                                                                                                                                                
英文名稱  Anti-APOBEC1 
中文名稱  載脂蛋白B-mRNA編輯酶復(fù)合物1抗體 
別    名  ABEC1_HUMAN; APOBEC 1; APOBEC1; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA editing enzyme complex 1; Apolipoprotein B mRNA-editing enzyme 1; BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR. 

詳細(xì)介紹:


濃    度  1mg/1ml 
規(guī) 格  0.2ml/200μg    
抗體來(lái)源  Rabbit  
克隆類型  polyclonal 
交叉反應(yīng)  Human, Horse  
產(chǎn)品類型  一抗    
研究領(lǐng)域  細(xì)胞生物 表觀遺傳學(xué)  
蛋白分子量  predicted molecular weight: 28kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human APOBEC1 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復(fù)) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關(guān)資料:


產(chǎn)品介紹 Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008].
Function : Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA.
Subunit : Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP. 
Subcellular Location : Cytoplasm.
Tissue Specificity : Expressed exclusively in the small intestine.
Similarity : Belongs to the cytidine and deoxycytidylate deaminase family.
Database links : UniProtKB/Swiss-Prot: P41238.3

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