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生命科學(xué)標(biāo)準(zhǔn)品
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產(chǎn)品編號(hào) |
英文名稱(chēng) |
CAS號(hào) |
包裝 |
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Y0698 |
Ivermectine |
70288-86-7 |
可根據(jù)客戶(hù)要求訂制 |
產(chǎn)品編號(hào)：Y0698
英文名稱(chēng)：Ivermectine
CAS號(hào) 70288-86-7
分析標(biāo)準(zhǔn)品
分子式 C48H74O14 分子量875.09
基本信息:
存貯條件儲(chǔ)存溫度 2-8°C
描述
產(chǎn)品介紹穩(wěn)定，在水中溶解度極低。
別名MK-933;MK-933;22,23-Dihydroavermectin B1
生化機(jī)理
Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM).
應(yīng)用Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.
